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1.
European Journal of Criminology ; 20(3):996-1015, 2023.
Article in English | ProQuest Central | ID: covidwho-20235846

ABSTRACT

The advent of COVID-19 prompted the enforced isolation of elderly and vulnerable populations around the world, for their own safety. For people in prison, these restrictions risked compounding the isolation and harm they experienced. At the same time, the pandemic created barriers to prison oversight when it was most needed to ensure that the state upheld the rights and wellbeing of those in custody. This article reports findings from a unique collaboration in Ireland between the Office of the Inspector of Prisons – a national prison oversight body – and academic criminologists. Early in the pandemic, they cooperated to hear the voices of people ‘cocooning' – isolated because of their advanced age or a medical vulnerability – in Irish prisons by providing journals to this cohort, analysing the data, and encouraging the Irish Prison Service to change practices accordingly. The findings indicated that ‘cocooners' were initially ambivalent about these new restrictions, both experiencing them as a punishment akin to solitary confinement, and understanding the goal of protection. As time passed, however, participants reported a drastic impact on their mental and physical health, and implications for their (already limited) agency and relationships with others, experienced more or less severely depending on staff and management practices. The paper also discusses the implications for prison practices during and following the pandemic, understanding isolation in the penological context, and collaboration between prison oversight bodies and academics.

3.
Radiat Phys Chem Oxf Engl 1993 ; 209: 110965, 2023 Aug.
Article in English | MEDLINE | ID: covidwho-2291034

ABSTRACT

Chest X-ray imaging is the most common X-ray imaging method for diagnosing coronavirus disease. The thyroid gland is one of the most radiation-sensitive organs of the body, particularly in infants and children. Therefore, it must be protected during chest X-ray imaging. Yet, because it has benefits and drawbacks, using a thyroid shield as protection during chest X-ray imaging is still up for debate.Therefore, this study aims to clarify the need for using a protective thyroid shield during chest X-ray imaging. This study was performed using different dosimeters (silica beads as a thermoluminescent dosimeter and an optically stimulated luminance dosimeter) embedded in an adult male ATOM dosimetric phantom. The phantom was irradiated using a portable X-ray machine with and without thyroid shielding. The dosimeter readings indicated that a thyroid shield reduced the radiation dose to the thyroid gland by 69% ± 18% without degrading the obtained radiograph. The use of a protective thyroid shield during chest X-ray imaging is recommended because its benefits outweigh the risks.

4.
IEEE Microwave Magazine ; 24(4):49-62, 2023.
Article in English | Scopus | ID: covidwho-2271974

ABSTRACT

Accurate characterization of biological matter, for example, in tissue, cells, and biological fluids, is of high importance. For example, early and correct detection of abnormalities, such as cancer, is essential as it enables early and effective type-specific treatment, which is crucial for mortality reduction [1]. Moreover, it is imperative to investigate the effectiveness and toxicity of pharmaceutical treatments before administration in clinical practice [2]. However, biological matter characterization still faces many challenges. State-of-the-art imaging and characterization methods have drawbacks, such as the requirement to attach difficult-to-find and costly labels to the biological target (e.g., COVID-19 rapid tests), expensive equipment (e.g., magnetic resonance imaging), low accuracy (e.g., ultrasound), use of ionizing radiation (e.g., X-rays), and invasiveness [3]. The characterization of biological matter using microwave (μW), millimeter-wave (mmW), and terahertz (THz) spectroscopy is a promising alternative: it is label-free, does not require ionizing radiation, and can be noninvasive. Moreover, there is a significant difference in how different biological materials absorb, reflect, and transmit electromagnetic (EM) waves [4] that is due to the difference in their dielectric properties. The dielectric properties are described by the frequency-dependent material parameter called the complex permittivity f, which expresses how the material responds to an external oscillating electric field. The complex permittivity of a material determines how the material absorbs, reflects, and transmits EM waves at different frequencies (Figure 1). Since each biological material's permittivity spectrum is different, it acts as an EM fingerprint. A material's complex permittivity can be calculated from the reflection and transmission of EM waves through the material, described by the S-parameters, which can be measured using a vector network analyzer (VNA) transmitting and receiving EM waves over a range of frequencies. The amplitude and phase of the transmitted and reflected EM waves at different frequencies are influenced by different underlying biological effects at different scales. That causes the entire spectrum to provide information from the supracellular to the molecular and even atomic scale. © 2000-2012 IEEE.

5.
Journal of Crystal Growth ; 610, 2023.
Article in English | Scopus | ID: covidwho-2257038

ABSTRACT

Recently, the silicon wafer producers, affected by Covid-19 and USA-China competition, looks for new production processes to increase the production. On the other hand, the common parts of CZ puller such as heater, crucible and thermal shield are optimized over time and now the common CZ process is reached to limitation for further improvement. Here, we propose a modified CZ method by adding a cooling tube into the growth zone. The new proposed Cz method is applied to the 8″ crystal growth process. A fully 3D transition model including energy equation, Navier–Stokes equation, surface-to-surface radiation heat transfer, moving mesh and thermal stress equations is implemented. The simulation is performed for both original and new CZ method. It was proved that the new CZ method increases the pulling speed up to 25 %. To ensure about the crystal quality, the thermal stress is compared between original and new proposed CZ method. Although it was found that the thermal stress increases about twice but still the maximum von Mises stress never exceeds the critical value 25 MPa. Additionally, the power consumption is also found to enhance maximum 2 kW under new conditions. To evaluate the model the interface and heater power for the original CZ puller is compared with industrial CZ process and it shows acceptable accuracy. © 2023 Elsevier B.V.

6.
Rheumatology (Oxford) ; 2023 Apr 05.
Article in English | MEDLINE | ID: covidwho-2279074

ABSTRACT

OBJECTIVES: To calculate the rates of COVID-19 infection and COVID-19-related death among people with rare autoimmune rheumatic diseases (RAIRD) during the second wave of the COVID-19 pandemic in England, and describe the impact of corticosteroids on outcomes. METHODS: Hospital Episode Statistics data were used to identify people alive 01 August 2020 with ICD-10 codes for RAIRD from the whole population of England. Linked national health records were used to calculate rates and rate ratios of COVID-19 infection and death up to 30 April 2021. Primary definition of COVID-19-related death was mention of COVID-19 on the death certificate. NHS Digital and Office for National Statistics general population data were used for comparison. The association between 30-day corticosteroid usage and COVID-19-related death, COVID-19-related hospital admissions and all-cause deaths were also described. RESULTS: Of 168 330 people with RAIRD, 9,961 (5.92%) had a positive COVID-19 PCR test. The age-standardised infection rate ratio between RAIRD and the general population was 0.99 (95% CI 0.97-1.00). 1,342 (0.80%) people with RAIRD died with COVID-19 on their death certificate and the age-sex-standardised mortality rate for COVID-19-related death was 2.76 (2.63-2.89) times higher than in the general population. There was a dose-dependent relationship between 30-day corticosteroid usage and COVID-19-related death. There was no increase in deaths due to other causes. CONCLUSIONS: During the second wave of COVID-19 in England, people with RAIRD had the same risk of COVID-19 infection but a 2.76-fold increased risk of COVID-19-related death compared with the general population, with corticosteroids associated with increased risk.

7.
Cell Rep ; 42(4): 112307, 2023 Mar 15.
Article in English | MEDLINE | ID: covidwho-2249129

ABSTRACT

Animal reservoirs of sarbecoviruses represent a significant risk of emergent pandemics, as evidenced by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. Vaccines remain successful at limiting severe disease and death, but the potential for further coronavirus zoonosis motivates the search for pan-coronavirus vaccines. This necessitates a better understanding of the glycan shields of coronaviruses, which can occlude potential antibody epitopes on spike glycoproteins. Here, we compare the structure of 12 sarbecovirus glycan shields. Of the 22 N-linked glycan attachment sites present on SARS-CoV-2, 15 are shared by all 12 sarbecoviruses. However, there are significant differences in the processing state at glycan sites in the N-terminal domain, such as N165. Conversely, glycosylation sites in the S2 domain are highly conserved and contain a low abundance of oligomannose-type glycans, suggesting a low glycan shield density. The S2 domain may therefore provide a more attractive target for immunogen design efforts aiming to generate a pan-coronavirus antibody response.

8.
Hedianzixue Yu Tance Jishu/Nuclear Electronics and Detection Technology ; 42(2):340-344, 2022.
Article in Chinese | Scopus | ID: covidwho-2170087

ABSTRACT

According to the epidemic prevention requirements of the coronavirus disease 2019 and technical requirements of blood irradiators, a new type of blood irradiator based on X band 2.5 MeV electron linear accelerator has been developed at Xihua University. In this paper, MCNP5 was used to optimize the design of flattening filter and shielding of X ray beam of the blood irradiator, and relevant experimental verification was carried out. After optimization design, the X ray beam flatness of the blood irradiator is improved from 59.8% to 92.4%, the weight of the shielding structure is reduced, and the maximum dose rate at 50 mm around the shielding body is 1 μSv/h, which is much better than the Chinese national standard of blood irradiator. © 2022, Editorial Board of Nuclear Electronics & Detection Tech. All right reserved.

9.
Future Healthc J ; 9(3): 291-294, 2022 Nov.
Article in English | MEDLINE | ID: covidwho-2203508

ABSTRACT

Background: Shielding during the COVID-19 pandemic impacted postgraduate medical training, likely affecting between 7% and 14% of trainees. We examine the burden of shielding on this cohort and provide strategies for future working practices. Methods: Seventeen postgraduate doctors in training took part in non-incentivised, virtual focus groups or interviews. Focus group content underwent thematic analysis. Results were validated in subsequent focused interviews. Results: Shielding trainees reported guilt, limited support and occasionally stigmatisation. Rotational changes and returning to work were also difficult and led to contractual challenges. Departmental support, IT provision and proactivity were key to successful shielding. Early discussion with training bodies was deemed essential to plan objective onward progression. Conclusion: As we enter an era of endemic COVID-19, adjusted working practices will continue. Embedding successful working practices for shielding at national and local levels will minimise the long-term impact on postgraduate medical training.

10.
JMIR Public Health Surveill ; 7(9): e30460, 2021 09 20.
Article in English | MEDLINE | ID: covidwho-2141344

ABSTRACT

BACKGROUND: The UK National Health Service (NHS) classified 2.2 million people as clinically extremely vulnerable (CEV) during the first wave of the 2020 COVID-19 pandemic, advising them to "shield" (to not leave home for any reason). OBJECTIVE: The aim of this study was to measure the determinants of shielding behavior and associations with well-being in a large NHS patient population for informing future health policy. METHODS: Patients contributing to an ongoing longitudinal participatory epidemiology study (Longitudinal Effects on Wellbeing of the COVID-19 Pandemic [LoC-19], n=42,924) received weekly email invitations to complete questionnaires (17-week shielding period starting April 9, 2020) within their NHS personal electronic health record. Question items focused on well-being. Participants were stratified into four groups by self-reported CEV status (qualifying condition) and adoption of shielding behavior (baselined at week 1 or 2). The distribution of CEV criteria was reported alongside situational variables and univariable and multivariable logistic regression. Longitudinal trends in physical and mental well-being were displayed graphically. Free-text responses reporting variables impacting well-being were semiquantified using natural language processing. In the lead up to a second national lockdown (October 23, 2020), a follow-up questionnaire evaluated subjective concern if further shielding was advised. RESULTS: The study included 7240 participants. In the CEV group (n=2391), 1133 (47.3%) assumed shielding behavior at baseline, compared with 633 (13.0%) in the non-CEV group (n=4849). CEV participants who shielded were more likely to be Asian (odds ratio [OR] 2.02, 95% CI 1.49-2.76), female (OR 1.24, 95% CI 1.05-1.45), older (OR per year increase 1.01, 95% CI 1.00-1.02), living in a home with an outdoor space (OR 1.34, 95% CI 1.06-1.70) or three to four other inhabitants (three: OR 1.49, 95% CI 1.15-1.94; four: OR 1.49, 95% CI 1.10-2.01), or solid organ transplant recipients (OR 2.85, 95% CI 2.18-3.77), or have severe chronic lung disease (OR 1.63, 95% CI 1.30-2.04). Receipt of a government letter advising shielding was reported in 1115 (46.6%) CEV participants and 180 (3.7%) non-CEV participants, and was associated with adopting shielding behavior (OR 3.34, 95% CI 2.82-3.95 and OR 2.88, 95% CI 2.04-3.99, respectively). In CEV participants, shielding at baseline was associated with a lower rating of mental well-being and physical well-being. Similar results were found for non-CEV participants. Concern for well-being if future shielding was required was most prevalent among CEV participants who had originally shielded. CONCLUSIONS: Future health policy must balance the potential protection from COVID-19 against our findings that shielding negatively impacted well-being and was adopted in many in whom it was not indicated and variably in whom it was indicated. This therefore also requires clearer public health messaging and support for well-being if shielding is to be advised in future pandemic scenarios.


Subject(s)
COVID-19/prevention & control , Communicable Disease Control/methods , Mental Health/trends , Public Health/trends , Quarantine/psychology , Adult , Female , Health Policy , Humans , Longitudinal Studies , Male , Mental Health/legislation & jurisprudence , Middle Aged , Public Health/legislation & jurisprudence , SARS-CoV-2 , State Medicine , Surveys and Questionnaires , United Kingdom
11.
BMC Public Health ; 22(1): 2145, 2022 11 22.
Article in English | MEDLINE | ID: covidwho-2139211

ABSTRACT

BACKGROUND: The national shielding programme was introduced by UK Government at the beginning of the COVID-19 pandemic, with individuals identified as clinically extremely vulnerable (CEV) offered advice and support to stay at home and avoid all non-essential contact. This study aimed to explore the impact and responses of "shielding" on the health and wellbeing of CEV individuals in Southwest England during the first COVID-19 lockdown. METHODS: A two-stage mixed methods study, including a structured survey (7 August-23 October 2020) and semi-structured telephone interviews (26 August-30 September 2020) with a sample of individuals who had been identified as CEV and advised to "shield" by Bristol, North Somerset & South Gloucestershire (BNSSG) Clinical Commissioning Group (CCG). RESULTS: The survey was completed by 203 people (57% female, 54% > 69 years, 94% White British, 64% retired) in Southwest England identified as CEV by BNSSG CCG. Thirteen survey respondents participated in follow-up interviews (53% female, 40% > 69 years, 100% White British, 61% retired). Receipt of 'official' communication from NHS England or General Practitioner (GP) was considered by participants as the legitimate start of shielding. 80% of survey responders felt they received all relevant advice needed to shield, yet interviewees criticised the timing of advice and often sought supplementary information. Shielding behaviours were nuanced, adapted to suit personal circumstances, and waned over time. Few interviewees received community support, although food boxes and informal social support were obtained by some. Worrying about COVID-19 was common for survey responders (90%). Since shielding had begun, physical and mental health reportedly worsened for 35% and 42% of survey responders respectively. 21% of survey responders scored ≥ 10 on the PHQ-9 questionnaire indicating possible depression and 15% scored ≥ 10 on the GAD-7 questionnaire indicating possible anxiety. CONCLUSIONS: This research highlights the difficulties in providing generic messaging that is applicable and appropriate given the diversity of individuals identified as CEV and the importance of sharing tailored and timely advice to inform shielding decisions. Providing messages that reinforce self-determined action and assistance from support services could reduce the negative impact of shielding on mental health and feelings of social isolation.


Subject(s)
COVID-19 , General Practitioners , Humans , Female , Male , COVID-19/epidemiology , COVID-19/prevention & control , Pandemics , Communicable Disease Control , General Practitioners/psychology , Mental Health
12.
Viruses ; 14(11)2022 Oct 30.
Article in English | MEDLINE | ID: covidwho-2090370

ABSTRACT

Pregnant patients have increased morbidity and mortality in the setting of SARS-CoV-2 infection. The exposure of pregnant patients in New York City to SARS-CoV-2 is not well understood due to early lack of access to testing and the presence of asymptomatic COVID-19 infections. Before the availability of vaccinations, preventative (shielding) measures, including but not limited to wearing a mask and quarantining at home to limit contact, were recommended for pregnant patients. Using universal testing data from 2196 patients who gave birth from April through December 2020 from one institution in New York City, and in comparison, with infection data of the general population in New York City, we estimated the exposure and real-world effectiveness of shielding in pregnant patients. Our Bayesian model shows that patients already pregnant at the onset of the pandemic had a 50% decrease in exposure compared to those who became pregnant after the onset of the pandemic and to the general population.


Subject(s)
COVID-19 , SARS-CoV-2 , Pregnancy , Female , Humans , COVID-19/epidemiology , COVID-19/prevention & control , Pandemics , New York City/epidemiology , Bayes Theorem
13.
Front Oncol ; 12: 901426, 2022.
Article in English | MEDLINE | ID: covidwho-1997472

ABSTRACT

Background: Acute severe forms of COVID-19 infection are more likely in cancer patients and growing attention has been given to the persistent symptoms of the disease after severe COVID-19. However, mild illness is the dominant clinical presentation of COVID-19 infection. To investigate patients' behavior and the short- and longer-term pattern of the disease in cancer patients with mild COVID infection, a longitudinal online survey was conducted for 16 months during the pandemic in a large cohort of cancer patients from a French COVID-19 hot spot. An online questionnaire was administered at three time points between the first wave of the pandemic in France and the fourth wave. The questionnaire was completed by 1415 to 2224 patients, which queried patients' demographics, their behavior, and COVID infection patterns. Seventy percent of the patients were female, and 40% had a comorbid condition. More than one-third of the participants had breast cancer, and half were survivors. The rate of infection was 30% during wave 1 and 10% in wave 4; most patients had a mild COVID-19 infection. Twenty-five percent of infected patients during wave 4 did not seek medical advice. At wave 4, 87% of the patients received at least one dose of vaccine. Systematic compliance to shielding measures decreased over time. The short-term pattern of mild COVID changed between wave 1 and wave 4. Twenty-two percent of infected patients experienced persistent signs for more than 6 months with a negative impact on sleep, social behavior, and increased consumption of stress-relieving drugs. Our results showed a high prevalence of long-lasting symptoms in cancer patients with mild COVID-19 infection and inadequate behavior toward the disease and prevention measures among patients.

14.
Radiography (Lond) ; 28(3): 869-870, 2022 08.
Article in English | MEDLINE | ID: covidwho-1983858
15.
Rheumatology (Oxford) ; 61(8): 3161-3171, 2022 08 03.
Article in English | MEDLINE | ID: covidwho-1973248

ABSTRACT

OBJECTIVES: To calculate the rates of COVID-19 infection and COVID-19-related death among people with rare autoimmune rheumatic diseases (RAIRD) during the first wave of the COVID-19 pandemic in England compared with the general population. METHODS: We used Hospital Episode Statistics to identify all people alive on 1 March 2020 with ICD-10 codes for RAIRD from the whole population of England. We used linked national health records (demographic, death certificate, admissions and PCR testing data) to calculate rates of COVID-19 infection and death up to 31 July 2020. Our primary definition of COVID-19-related death was mention of COVID-19 on the death certificate. General population data from Public Health England and the Office for National Statistics were used for comparison. We also describe COVID-19-related hospital admissions and all-cause deaths. RESULTS: We identified a cohort of 168 680 people with RAIRD, of whom 1874 (1.11%) had a positive COVID-19 PCR test. The age-standardized infection rate was 1.54 (95% CI: 1.50, 1.59) times higher than in the general population. A total of 713 (0.42%) people with RAIRD died with COVID-19 on their death certificate and the age-sex-standardized mortality rate for COVID-19-related death was 2.41 (2.30-2.53) times higher than in the general population. There was no evidence of an increase in deaths from other causes in the RAIRD population. CONCLUSIONS: During the first wave of COVID-19 in England, people with RAIRD had a 54% increased risk of COVID-19 infection and more than twice the risk of COVID-19-related death compared with the general population. These increases were seen despite shielding policies.


Subject(s)
COVID-19 , Rheumatic Diseases , Autoimmune Diseases/complications , Autoimmune Diseases/mortality , COVID-19/mortality , COVID-19/therapy , Cause of Death , England/epidemiology , Hospitalization , Humans , Pandemics , Rheumatic Diseases/complications , Rheumatic Diseases/mortality
16.
Sustainability ; 14(13):7536, 2022.
Article in English | ProQuest Central | ID: covidwho-1934211

ABSTRACT

The aim of this study is to explore the relationship between the extensive application of technology and young people’s “withdrawal from nature”. Among them, “withdrawal from nature” is mainly manifested in a reduced connection with and concern for nature. Two rounds of semi-structured interviews were conducted with 101 young people from China. Thematic analysis was performed to analyze the interview data and resulted in three main themes: the “compensation”, “shifting” and “shielding” effects of technology. More specifically, the application of technology can partially make up for nature’s reduced role in the growth of young people, shift their concerns for ecological problems, and even affect their perception and evaluation of ecological destruction. Thus, it was proved that the application of technology has an impact on young people’s “withdrawal from nature”. This study supplemented the current research on the factors that influence young people’s “withdrawal from nature” and also provided inspiration for better establishing the connection between young people and nature.

17.
Int J Environ Res Public Health ; 19(12)2022 06 15.
Article in English | MEDLINE | ID: covidwho-1896862

ABSTRACT

In March 2020, individuals shielding from coronavirus reported high rates of distress. This study investigated whether fear of contamination (FoC) and use of government-recommended behaviours (GRB; e.g., handwashing and wearing masks) were associated with psychological distress during February 2021. An online cross-sectional questionnaire assessed psychological distress in three groups (shielding self, shielding other/s, and control), and those shielding others also completed an adapted measure of health anxiety (α = 0.94). The sample (N = 723) was predominantly female (84%) with a mean age of 41.72 (SD = 15.15). Those shielding (self) demonstrated significantly higher rates of health anxiety and FoC in comparison to other groups (p < 0.001). The use of GRB was significantly lower in controls (p < 0.001), with no significant difference between the two shielding groups (p = 0.753). Rates of anxiety were higher when compared to March 2020 findings, except for controls. Hierarchical regressions indicated FoC and GRB accounted for 24% of variance in generalised anxiety (p < 0.001) and 28% in health anxiety, however, the latter was a non-significant predictor in final models. Those shielding themselves and others during the pandemic have experienced sustained levels of distress; special consideration must be given to those indirectly affected. Psychological interventions should account for realistic FoC and the impact of government-recommended health behaviours, as these factors are associated with distress in vulnerable groups and may extend beyond the pandemic. Future research should focus on longitudinal designs to monitor and better understand the clinical needs of those shielding, and those shielding others post-pandemic.


Subject(s)
COVID-19 , Pandemics , Adult , Anxiety/epidemiology , Anxiety/psychology , COVID-19/epidemiology , Cross-Sectional Studies , Depression/psychology , Family , Female , Humans , Male , Mental Health , SARS-CoV-2
18.
EnvironmentAsia ; 15(Special Issue):93-99, 2022.
Article in English | Scopus | ID: covidwho-1876221

ABSTRACT

Chest X-ray is the first imaging procedure that play an important role in identification of COVID-19 as well as medical diagnostic and treatment of COVID-19 patients, in order to increase recovery rates and to lower fatality rates. Regardless of their environmental disadvantages and high toxicity, lead aprons are important materials for personal protection of physicians and patients from X-ray radiation during medical operations. Typically, for standard lead protective aprons, the transmittance values for lite-lead (LL) and regular lead (RL) were approximately 18 % and 17 %, respectively. With an aim to find new materials possibly to replace toxic lead-shielding products, in this study, an environmentally friendly and flexible fabric-based radiation shielding material was manufactured. Polyester fabric was coated by Bi2O3 nano particles using a simple, scalable, and cost-effective method to deposit the nano-particles onto the textile fabric surface. This application method allows the potential production of nano-Bi2O3 coated polyester fabric at the maximum %uptake of 45 and mass per unit area of 0.41 g/cm2 for 1 layer fabric. Radiation attenuation of the fabric increased with the numbers of fabric layers. Five layers of the fabric showed X-ray transmission of approximately 85% when measured at 80 kVp tube voltage, the medical application standard. To increase X-ray protection ability, the nano-Bi2O3 coated polyester fabric surface was recoated with PVA/ Bi2O3 coating composites using K-hand coater. The potential application of the recoated fabric as environmentally friendly and flexible fabric-based radiation shielding material for X-ray attenuation was also demonstrated. The 5-layer PLA/nano-Bi2O3 coated fabric showed the lowest X-ray transmission of 65.7%, implying the moderate improvement of shielding ability. This could lead to an X-ray protection textile garment that can potentially replace lead aprons. © 2022, Thai Society of Higher Eduation Institutes on Environment. All rights reserved.

19.
34th Australasian Joint Conference on Artificial Intelligence, AI 2021 ; 13151 LNAI:332-343, 2022.
Article in English | Scopus | ID: covidwho-1782718

ABSTRACT

There are many ways machine learning and big data analytics are used in the fight against the COVID-19 pandemic, including predictions, risk management, diagnostics, and prevention. This study focuses on predicting COVID-19 patient shielding—identifying and protecting patients who are clinically extremely vulnerable from coronavirus. This study focuses on techniques used for the multi-label classification of medical text. Using the information published by the United Kingdom NHS and the World Health Organisation, we present a novel approach to predicting COVID-19 patient shielding as a multi-label classification problem. We use publicly available, de-identified ICU medical text data for our experiments. The labels are derived from the published COVID-19 patient shielding data. We present an extensive comparison across 12 multi-label classifiers from the simple binary relevance to neural networks and the most recent transformers. To the best of our knowledge this is the first comprehensive study, where such a range of multi-label classifiers for medical text are considered. We highlight the benefits of various approaches, and argue that, for the task at hand, both predictive accuracy and processing time are essential. © 2022, Springer Nature Switzerland AG.

20.
Br J Psychiatry ; 221(4): 637-643, 2022 10.
Article in English | MEDLINE | ID: covidwho-1775389

ABSTRACT

BACKGROUND: During the COVID-19 pandemic, older and clinically vulnerable people were instructed to shield or stay at home. Policies restricting social contact and human interaction pose a risk to mental health, but we know very little about the impact of shielding and stay-at-home orders on the mental health of older people. AIMS: To understand the extent to which shielding contributes to poorer mental health. METHOD: We used longitudinal data from wave 9 (2018/2019) and two COVID-19 sub-studies (June/July 2020; November/December 2020) of the English Longitudinal Study of Ageing, and constructed logistic and linear regression models to investigate associations between patterns of shielding during the pandemic and mental health, controlling for sociodemographic characteristics, pre-pandemic physical and mental health, and social isolation measures. RESULTS: By December 2020, 70% of older people were still shielding or staying at home, with 5% shielding throughout the first 9 months of the pandemic. Respondents who shielded experienced worse mental health. Although prior characteristics and lack of social interactions explain some of this association, even controlling for all covariates, those shielding throughout had higher odds of reporting elevated depressive symptoms (odds ratio 1.87, 95% CI 1.22-2.87) and lower quality of life (ß = -1.28, 95% CI -2.04 to -0.52) than those who neither shielded nor stayed at home. Shielding was also associated with increased anxiety. CONCLUSIONS: Shielding seems associated with worse mental health among older people, highlighting the need for policy makers to address the mental health needs of those who shielded, both in the current pandemic and for the future.


Subject(s)
COVID-19 , Aged , Aging , COVID-19/epidemiology , COVID-19/prevention & control , Humans , Longitudinal Studies , Mental Health , Pandemics/prevention & control , Quality of Life , SARS-CoV-2
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